In a new study published in the scientific journal Science Advances, researches at Uppsala University have demonstrated that just one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans.
In a world of chronic sleep deprivation and shift work, as well as a rising level of obesity, this makes perfect sense.
Epidemiological studies in the past have shown a corollary between chronic sleep loss and shift work with obesity and type 2 diabetes.
Other studies have demonstrated the association between disrupted sleep, fat accumulation, and a reduction in muscle mass.
This most recent work at Uppsala University studied 15 normal weight individuals, and had them participate in two different lab sessions.
In one, participants slept a normal 8 hours or more, and in another, they were kept awake all night. The morning after the all-nighter, small tissue biopsies were performed from subcutaneous fat and skeletal muscle.
The sleep deprived tissue demonstrated changes in DNA methylation, which is one key in regulation of gene expression. But the big take away here is that the changes in methylation only in the adipose tissue.
Take this from the lab into real life: imagine what one night of partying really does internally.
Get Your Sleep Right
A restful and complete night sleep is a huge factor in performance. It's also the lowest hanging fruit we have in performance enhancement.
Take your sleep seriously, and follow our sleep hygiene primer to get the most out of the time you spend under the covers.